RESEARCH TOPICS

1. Identification of genetic factors predisposing to psychiatric disorders, mainly schizophrenia and substance use disorders

2. Estimation of individual polygenic risk scores to develop psychiatric disorders due to common variants along the genome

3. Association of polygenic risk scores with clinical features, such as symptoms severity and comorbidity

4. Gene-set enrichment analysis to identify functionally related gene-sets involved in susceptibility to psychiatric disorders

5. Identification of rare genetic variants of high impact to develop psychiatric disorders

6. Interaction/correlation between genetic and environmental factors in susceptibility to psychiatric disorders

7. Shared genetic susceptibility between different psychiatric disorders and its involvement in comorbidity, mainly between substance use disorders and other psychiatric disorder (i.e. dual diagnosis)

8. Implications of shared genetic susceptibility between different psychiatric disorders for the hierarchical structure of psychopatology